Drug intelligence / Profile preview

Zao Zhi An Shen Tie

Development stage
Unknown
Lead developer
Huawei Technologies
Modality
Transdermal Patches → Device-based Delivery → Drug Delivery Systems
Administration
Topical, Transdermal
01

Overview

Zao Zhi An Shen Tie is a traditional Chinese medicine (TCM) topical patch formulated for the treatment of insomnia, anxiety, and sleep-related disturbances. The preparation typically contains extracts from *Semen Ziziphi Spinosae* (Sour Jujube Seed) and *Fructus Gardeniae* (Gardenia Fruit), along with other supportive herbs like *Radix Polygalae*. It is designed for acupoint application (e.g., to the Shenque or Yongquan points), where it delivers active phytochemicals such as jujubosides and geniposide transdermally. These components are believed to exert sedative effects by clearing internal heat and nourishing the heart, effectively calming the spirit (An Shen). It is widely manufactured in China, notably by Wuhan Huawei Technology, and is often categorized as an external-use TCM product or a medical device for acupoint therapy.

Brand names
Zao Zhi An Shen Tie
Other names
Jujube Gardenia Calming Patch枣栀安神贴
02

Targets

GABRA1 (Gamma-aminobutyric acid type A receptor alpha 1 subunit)5-HT (Serotonin receptors)

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