Drug intelligence / Profile preview

Zaobai Anshen Granules

Development stage
Unknown
Lead developer
Lianyungang Kanion
Modality
Small Molecules
Administration
Oral
01

Overview

Zaobai Anshen Granules is a Traditional Chinese Medicine (TCM) developed by Jiangsu Kanion Pharmaceutical Co., Ltd. for the treatment of chronic insomnia. It is specifically indicated for patients presenting with the TCM syndrome of heart and spleen deficiency, which manifests as difficulty falling asleep, dream-disturbed sleep, and fatigue. The formulation is a multi-herb compound, with key components including Ziziphi Spinosae Semen (Suanzaoren) and Platycladi Semen (Baiziren), which are traditionally recognized for their sedative and hypnotic properties. Pharmacologically, these ingredients are believed to modulate the central nervous system, particularly through the GABAergic pathway, to promote relaxation and improve sleep architecture. The drug received marketing approval from the China National Medical Products Administration (NMPA) in December 2023 following successful clinical trials that demonstrated its safety and efficacy in improving sleep quality scores.

Brand names
Zaobai Anshen Granules
Other names
Zaobai Anshen Keli
02

Targets

GABA-B (Gamma-aminobutyric acid receptor type B)

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