Drug intelligence / Profile preview

zaoshi huatan recipe

Development stage
Unknown
Lead developer
Guangzhou University of Chinese Medicine
Modality
Small Molecules
Administration
Oral
01

Overview

Zaoshi Huatan recipe is a Traditional Chinese Medicine (TCM) herbal formulation based on the principles of drying dampness and resolving phlegm. It is frequently derived from the classic 'Er Chen Tang' base, typically incorporating herbs such as *Rhizoma Pinelliae Praeparata*, *Pericarpium Citri Reticulatae*, *Poria*, and *Rhizoma Atractylodis*. In modern clinical research, it is primarily indicated for the treatment of Polycystic Ovary Syndrome (PCOS) and metabolic syndrome, where it is used to alleviate insulin resistance and endocrine dysfunction. The recipe is also utilized in respiratory medicine for Chronic Obstructive Pulmonary Disease (COPD) and chronic bronchitis to manage airway mucus hypersecretion. Its pharmacological action involves the regulation of the PI3K/Akt signaling pathway and the inhibition of pro-inflammatory cytokines such as TNF-α and IL-6.

Other names
Zaoshi Huatan decoctionZao Shi Hua Tan FangDrying Dampness and Resolving Phlegm formulaZao Shi Hua Tan Tang
02

Targets

PIK3CA (Phosphoinositide 3-kinase alpha)IL-6 (Interleukin 6)AKT1 (Proto-oncogene serine/threonine-protein kinase Akt1)

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