Drug intelligence / Profile preview

zaozhu yinchen decoction

Development stage
Preclinical
Modality
Small Molecules
Administration
Oral
01

Overview

Zaozhu Yinchen Decoction (ZZYC) is a Traditional Chinese Medicine (TCM) formula primarily investigated for its therapeutic potential in treating non-alcoholic steatohepatitis (NASH). The decoction is typically composed of herbal ingredients such as *Artemisia capillaris* (Yinchen) and *Atractylodes lancea* (Zaozhu), which are traditionally used to clear damp-heat and strengthen the spleen. Research indicates that ZZYC exerts its effects by regulating the recruitment and suppressive function of myeloid-derived suppressor cells (MDSCs) in the liver, thereby modulating the inflammatory microenvironment and reducing hepatic steatosis and injury.

Other names
Zaozhu Yinchen decoctionZZYC decoction

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