Drug intelligence / Profile preview

ZARS Vitamin D3

Development stage
Unknown
Lead developer
Apotex
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules
Administration
Oral
01

Overview

ZARS Vitamin D3 is an oral nutritional supplement developed by ZARS Pharma, containing cholecalciferol (Vitamin D3). It is indicated for the treatment of Vitamin D deficiency and provides supportive care for bone health and immune function. As a precursor to the active form of Vitamin D, cholecalciferol is metabolized to calcitriol, which binds to the Vitamin D receptor (VDR) to regulate calcium and phosphate homeostasis, promote intestinal calcium absorption, and modulate immune system activity. The product is marketed in Pakistan as part of a consumer health portfolio, with a high-potency branded version known as DELTAZARS.

Brand names
DELTAZARS
Other names
cholecalciferolVitamin D3
02

Targets

RXRA (Retinoid X receptor alpha)RBD (SARS-CoV-2 spike receptor-binding domain)TMPRSS2 (Transmembrane protease serine 2)VDR (Vitamin D receptor)ACE2 (Angiotensin-converting enzyme 2)

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