Drug intelligence / Profile preview

ZE77-0273

Development stage
Preclinical
Lead developer
Eilean Therapeutics
Modality
Small Molecules
Administration
Not Specified
01

Overview

ZE77-0273 is a reversible small-molecule drug candidate developed by Eilean Therapeutics. It acts as a pan-EGFR inhibitor, demonstrating broad activity against resistance mutations in EGFR-mutant non-small cell lung cancer (NSCLC) and has a high selectivity index versus wild-type EGFR. It is designed to be brain- and lung-permeable, offering an excellent safety and tolerability profile[1][8].

Brand names
ZE77-0273ZE-77-0273ZE 77-0273
Other names
ZE77-0273ZE-77-0273ZE 77-0273
02

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