Drug intelligence / Profile preview

zedoary turmeric oil

Development stage
Unknown
Modality
Classical Binding Small Molecules → Small Molecules
Administration
Intravenous, Topical, Inhalation
01

Overview

Zedoary turmeric oil is a volatile essential oil extracted from the rhizome of Curcuma zedoaria (zedoary), a plant in the ginger family. It is used in traditional medicine and as an ingredient in some pharmaceutical preparations. The oil contains various bioactive compounds with reported anti-inflammatory[2][6], antimicrobial[1], antiviral[3], and antitumor properties[5]. Mechanistically, it has been shown to induce apoptosis and senescence in cancer cells by upregulating proteins such as p16, p21, and p53 and activating ERK phosphorylation pathways[5]. In clinical settings—particularly in China—it is used as an injectable preparation for conditions like viral encephalitis (often combined with ganciclovir and interferon)[3] and acute lung injury/respiratory inflammation[2][6]. It also has applications for digestive complaints (colic, indigestion), pain relief (including arthritis), gynecological diseases such as vulvitis or colpitis[7], mosquito repellent use when applied topically[1], and emotional wellness via aromatherapy. Its broad pharmacological actions are attributed to its complex mixture of sesquiterpenes and other phytochemicals.

Brand names
Zedoary Turmeric Oil InjectionZeodaria Essential OilNar Kachur Essential Oil
Other names
Curcuma zedoaria oilWhite Turmeric Essential OilHuile de ZédoaireZeodary OilZitweröl
02

Targets

PF4 (Platelet factor 4)Cyp (Cyclophilin family)ERK/MAPK (Extracellular signal-regulated kinase/Mitogen-activated protein kinase pathway kinases)

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