Drug intelligence / Profile preview

Zeel

Development stage
Phase 3
Lead developer
Heel
Administration
Oral, Intraarticular, Intramuscular, Subcutaneous
01

Overview

Zeel is a homeopathic combination remedy used for the temporary relief of symptoms associated with osteoarthritis, including mild to moderate pain, articular stiffness, and inflammation. It contains a mix of botanical, mineral, and animal-derived substances. The mechanism of action is not fully understood but is believed to involve inhibition of cartilage-destroying enzymes and stimulation of growth factors that protect cartilage. Zeel is often used as an alternative to NSAIDs and steroids for pain management. It was developed by Heel and is manufactured by Hameln Pharma GmbH, Biologische Heilmittel Heel, and MediNatura. Zeel is not FDA-approved and is considered an unapproved drug by the FDA.

Brand names
Zeel
Other names
Zeel comp. N
02

Targets

PTGS2 (Prostaglandin-Endoperoxide Synthase 2)ALOX12 (Arachidonate 12-lipoxygenase, 12S type)PGHS-1 (Prostaglandin G/H Synthase 1)

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