Zengye decoction

Zengye decoction is a classic traditional Chinese medicine (TCM) herbal formula composed of Radix Scrophulariae (Xuanshen), Ophiopogon japonicus (Maidong), and Rehmannia glutinosa (Shengdihuang)[3][4][7]. Traditionally, it is used to "moisten the intestines," increase body fluids, and relieve dryness-related symptoms such as constipation, thirst, and dry tongue[1][3]. Modern research indicates that Zengye decoction exerts its effects through multiple mechanisms including modulation of aquaporin expression in the colon, regulation of gut microbiota composition and metabolism, improvement of insulin sensitivity via the Akt signaling pathway, and anti-inflammatory actions[1][2][5]. It has been studied for use in conditions such as slow transit constipation (STC), primary Sjögren’s syndrome, severe acute pancreatitis with acute kidney injury, type 2 diabetes mellitus with yin deficiency syndromes, and other dryness-related disorders[1][3][4][5].

Other names

ZYD