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Zenstral PMS
- Development stage
- Preclinical
- Lead developer
- University Lab Technologies
- Modality
- Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules, Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules
- Administration
- Oral
01
Overview
**Zenstral PMS** is an oral fixed-dose nutraceutical caplet developed initially by University Lab Technologies and subsequently promoted by University Health Industries for premenstrual syndrome. The product combines standardized *Vitex agnus-castus* extract, magnesium oxide, and pyridoxine. Its proposed activity is driven principally by chasteberry's dopaminergic and pituitary-related effects, while magnesium and vitamin B6 provide nutritional support relevant to neuromuscular and neurotransmitter function. Public promotional materials described it as a patent-pending supplement for relief of PMS-associated physical and cyclical mood symptoms, rather than as an approved pharmaceutical treatment. ([businesswire.com](https://www.businesswire.com/news/home/20080428005198/en/University-Health-Industries-Launches-National-Television-Commercial))
- Brand names
- Zenstral PMS
02
Targets
DRD2 (Dopamine D2 Receptor)
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