Drug intelligence / Profile preview

ZEPIZURE

Development stage
Preclinical
Lead developer
Crossject
Modality
Small Molecules
Administration
Intramuscular
01

Overview

ZEPIZURE is an emergency treatment for epileptic seizures, particularly status epilepticus, developed by Crossject. It consists of midazolam delivered via the ZENEO® needle-free auto-injector platform. This innovative delivery system allows for rapid, intramuscular administration by patients or untrained caregivers, even through clothing, aiming to provide faster and more consistent absorption of midazolam compared to traditional methods like intranasal administration. The drug is designed to quickly suppress seizures by enhancing inhibitory neurotransmission in the brain.

Brand names
ZEPIZUREZEPIZURE Junior
Other names
midazolamZENEO midazolam
02

Targets

GABRR (GABA-A receptor subunit rho)

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