Drug intelligence / Profile preview

Zepvog

Development stage
Unknown
Lead developer
Merlion Lifescience
Modality
Small Molecules
Administration
Oral
01

Overview

**Zepvog** is an oral fixed-dose antidiabetic combination product developed and marketed by Merlion Lifescience for glycemic control in **type 2 diabetes mellitus**. It contains voglibose and metformin hydrochloride: voglibose reversibly inhibits intestinal alpha-glucosidases, delaying carbohydrate digestion and postprandial glucose absorption, while metformin suppresses hepatic glucose production and improves peripheral insulin sensitivity, in part through activation of AMP-activated protein kinase signaling. The marketed product is a sustained-release tablet containing metformin 500 mg and voglibose 0.3 mg.

Brand names
Zepvog
Other names
metformin + voglibose
02

Targets

Sucrase-IsomaltaseAMPK (Adenosine monophosphate–activated protein kinase)

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