zeta-stat

ZETA-STAT is a **small molecule inhibitor** specifically targeting the zeta isoform of protein kinase C (PKC-ζ). It is chemically known as 1,3,6-naphthalenetrisulfonic acid. ZETA-STAT demonstrates selective inhibition of PKC-ζ with an IC50 of 5 μM, exhibiting minimal inhibition (13% at 20 μM) against other PKC isoforms such as PKC-I. The compound is primarily used in biochemical research to probe the role of PKC-ζ in various cellular signaling pathways, including those relevant to cell differentiation, proliferation, and survival[9]. No therapeutic indication or clinical development in humans has been reported.

Brand names

ZETA-STAT

Other names

1,3,6-naphthalenetrisulfonic acidNSC37044NSC-37044NSC 37044