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ZetaMAST
- Development stage
- Preclinical
- Lead developer
- ZetaGen
- Modality
- Small Molecules
- Administration
- Injectable, Intratumoral
01
Overview
ZetaMAST is an investigational small molecule therapeutic developed by Zetagen Therapeutics for the treatment of metastatic soft tissue lesions. It is based on the company's proprietary platform technology, originally licensed from the State University of New York, which utilizes strontium-based formulations to modulate the tumor microenvironment. While the company's lead asset, ZetaMet, is a drug-device combination targeting bone metastases, ZetaMAST is specifically optimized for delivery into soft tissue tumors. The therapy is designed to be administered via percutaneous injection directly into metastatic lesions, where it aims to disrupt oncogenic signaling within the metastatic niche and inhibit tumor progression.
- Brand names
- ZetaMAST
- Other names
- ZetaMAST
02
Targets
CaSR (Extracellular calcium-sensing receptor)
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