Drug intelligence / Profile preview

ZF2001 + tetravalent influenza virus lysis vaccine

Development stage
Unknown
Lead developer
Anhui Zhifei Longcom Biopharmaceutical
Modality
Recombinant Proteins and Enzymes, Vaccines & Immunotherapeutics
Administration
Intramuscular
01

Overview

ZF2001 + tetravalent influenza virus lysis vaccine is a co-administration regimen or combination product consisting of the recombinant protein subunit COVID-19 vaccine ZF2001 (Zifivax) and a tetravalent inactivated split-virion influenza vaccine. ZF2001, developed by Anhui Zhifei Longcom, utilizes the receptor-binding domain (RBD) of the SARS-CoV-2 spike protein produced in Chinese Hamster Ovary (CHO) cells and is adjuvanted with aluminum hydroxide. The tetravalent influenza component contains hemagglutinin from four seasonal influenza strains (typically A/H1N1, A/H3N2, and two B lineages). This combination is primarily studied to evaluate the safety and immunogenicity of simultaneous vaccination against both COVID-19 and seasonal influenza, aiming to simplify immunization schedules and improve compliance during overlapping outbreaks.

Brand names
Zifivax
Other names
recombinant novel coronavirus vaccine (CHO cell)tetravalent influenza virus lysis vaccinetetravalent influenza split vaccinerecombinant COVID-19 vaccine (CHO cell) combined with tetravalent influenza vaccine
02

Targets

RBD (SARS-CoV-2 spike receptor-binding domain)

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