Drug intelligence / Profile preview

ZG2273

Development stage
Preclinical
Lead developer
Suzhou Zelgen Biopharmaceuticals
Modality
Bispecific Antibodies → Multispecific Antibodies → Engineered Antibody Formats → Antibody-Based Therapeutics, Small Molecules
01

Overview

ZG2273 is an early-stage preclinical drug candidate being developed by Suzhou Zelgen Biopharmaceuticals (Zelgen). The program is part of Zelgen's portfolio of therapies discovered using its AI-driven drug discovery platform and structure-activity relationship (SAR) screening methodologies, which are designed to identify small-molecule drugs for traditionally 'undruggable' biological targets. While Zelgen's broader pipeline includes advanced biologics such as T-cell engagers and bispecific or multispecific antibodies, ZG2273 is specifically associated with the company's small-molecule discovery efforts. As of current public disclosures, the specific biological target, mechanism of action, and intended therapeutic indications for ZG2273 remain proprietary and have not been released.

02

Targets

HRAS (H-Ras protein)

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