Drug intelligence / Profile preview

zhaqu cordyceps liquid

Development stage
Preclinical
Lead developer
School of Medical Information Engineering, Chengdu University of Traditional Chinese Medicine
Administration
Oral
01

Overview

Zhaqu cordyceps liquid is an oral liquid preparation made from fermented Cordyceps, a fungus used in Traditional Chinese Medicine. It is being developed by the School of Medical Information Engineering at Chengdu University of TCM for the treatment of insomnia. [7] A clinical trial (ChiCTR2100051187) has studied its effects on primary insomnia, showing that the fermented Cordyceps sinensis broth significantly improved sleep outcomes compared to a placebo. [3, 5] The active components in Cordyceps, such as cordycepin (an adenosine analogue) and adenosine itself, are believed to contribute to its therapeutic effects on sleep. [3, 4] Animal studies suggest that cordycepin may increase non-rapid eye movement (NREM) sleep by acting on adenosine receptors (A1, A2A, and A2B), particularly in the hypothalamus. [3, 9]

Other names
Zhaqu cordyceps liquid扎曲虫草菌液
02

Targets

ADORA1 (Adenosine receptor A1 subtype)ADORA2A (Adenosine A₂A Receptor)ADORA2B (Adenosine A2B receptor)ADORA3 (Adenosine A3 receptor)

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