Drug intelligence / Profile preview

Zhejiang Univ. of Technology cathepsin L (CTSL) compound B5

Development stage
Unknown
Lead developer
Zhejiang University of Technology
01

Overview

Zhejiang Univ. of Technology cathepsin L (CTSL) compound B5: sourced facts only. name: "In addition, B5 effectively inhibited CTSL enzymatic activity, with an IC50 value of 5.52 μM." [PMID:41653775]; target: "In addition, B5 effectively inhibited CTSL enzymatic activity, with an IC50 value of 5.52 μM." [PMID:41653775]; developer: "College of Pharmaceutical Sciences, Zhejiang University of Technology, Hangzhou, 310014, PR China." [PMID:41653775]; stage: "In LPS-induced ALI mouse model, treatment with B5 (20 mg/kg) significantly reduced inflammatory cell infiltration into lung tissue, thereby markedly alleviating lung injury." [PMID:41653775]

02

Targets

pro-CTSL (Cathepsin L)

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