Zhejiang Univ. of Technology hMAO-B compound 11n

Zhejiang Univ. of Technology hMAO-B compound 11n: sourced facts only. name: "Compound 11n emerged as the most effective anti-AD lead compound with a pFe3+ value of 18.51, along with selective hMAO-B inhibitory activity (IC50 = 0.79 ± 0.05 μM, SI > 25.3)." [PMID:37690318]; target: "Compound 11n emerged as the most effective anti-AD lead compound with a pFe3+ value of 18.51, along with selective hMAO-B inhibitory activity (IC50 = 0.79 ± 0.05 μM, SI > 25.3)." [PMID:37690318]; developer: "College of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou, PR China." [PMID:37690318]; stage: "Moreover, compound 11n exhibited ideal blood-brain barrier (BBB) permeability in the parallel artificial membrane permeation assay (PAMPA), and significantly improved scopolamine-induced cognitive and memory impairment in mice behavioral experiments." [PMID:37690318]