Zhejiang Univ. of Technology hMAO-B compound 16d

Zhejiang Univ. of Technology hMAO-B compound 16d: sourced facts only. name: "Among these compounds, 16d has emerged as the most potent hMAO-B inhibitor with an IC50 value of 67.3 nM, comparable to safinamide (IC50 = 42.6 nM) in vitro." [PMID:38838545]; target: "Among these compounds, 16d has emerged as the most potent hMAO-B inhibitor with an IC50 value of 67.3 nM, comparable to safinamide (IC50 = 42.6 nM) in vitro." [PMID:38838545]; developer: "College of Pharmaceutical Science, Zhejiang University of Technology, Hangzhou, 310014, China." [PMID:38838545]; stage: "In the MPTP-induced PD mouse model, 16d significantly alleviated the motor impairment, especially muscle relaxation and motor coordination." [PMID:38838545]