Zhejiang Univ. ROCK2 compound 10d

Zhejiang Univ. ROCK2 compound 10d: sourced facts only. name: "Exploiting this structural feature through virtual screening led to the discovery of compound 10d, a potent ROCK2 inhibitor with markedly improved selectivity compared to the reference compound KD025." [PMID:41574563]; target: "Exploiting this structural feature through virtual screening led to the discovery of compound 10d, a potent ROCK2 inhibitor with markedly improved selectivity compared to the reference compound KD025." [PMID:41574563]; developer: "Institute of Marine Biology and Pharmacology, Ocean College, Zhejiang University, Zhoushan 316021, China." [PMID:41574563]; stage: "In a mouse model of MC903-induced AD, 10d effectively suppressed inflammation and achieved therapeutic efficacy superior to the model group, while maintaining a favorable safety profile." [PMID:41574563]