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zhenggong capsule
- Development stage
- Unknown
- Lead developer
- Lianyungang Kanion
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
Zhenggong Capsule is a Traditional Chinese Medicine (TCM) preparation developed by Jiangsu Kanion Pharmaceutical Co., Ltd., specifically for the treatment of endometriosis. It is designed to treat the "Qi stagnation and blood stasis" syndrome, a common TCM classification for patients presenting with dysmenorrhea, chronic pelvic pain, and adnexal masses. The formulation consists of multiple herbal components that work synergistically to promote blood circulation, resolve stasis, and provide analgesic effects. Pharmacologically, Zhenggong Capsule has been shown to inhibit the expression of pro-inflammatory cytokines such as TNF-alpha and IL-6, and reduce levels of vascular endothelial growth factor (VEGF), thereby potentially inhibiting the growth and vascularization of ectopic endometrial tissue. It has undergone Phase II and Phase III clinical trials in China, demonstrating efficacy in reducing pain scores and lesion size with a favorable safety profile compared to conventional hormonal treatments.
- Brand names
- Zhenggong Capsule
- Other names
- Zhenggong Jiaonang正宫胶囊
02
Targets
TNFA (Tumor necrosis factor alpha (soluble))VEGFA (Vascular endothelial growth factor A)
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