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Zhengqi tablets
- Development stage
- Unknown
- Lead developer
- Shanghai Hutchison Pharmaceuticals
- Modality
- Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
- Administration
- Oral
01
Overview
Zhengqi tablets (ZQP) are a modernized traditional Chinese medicine (TCM) herbal patent preparation developed and manufactured by Shanghai Hutchison Pharmaceuticals. Derived from the classical 'Huoxiang Zhengqi Powder' from the Song-dynasty text 'Taiping Huimin Ju Fang', the formulation has been refined to improve efficacy and safety. It is composed of multiple herbal extracts, including Pogostemon cablin oil, Radix aucklandiae, Atractylodes lancea, Magnolia officinalis, Pinellia ternate, orange peel, Poria cocos, perilla leaf oil, Zingiber officinale, and Glycyrrhiza uralensis. Zhengqi tablets are primarily indicated for gastrointestinal colds, dispelling dampness, and harmonizing the stomach and spleen. Additionally, they have been recommended for asymptomatic COVID-19 infections by the 2022 Shanghai expert consensus on TCM diagnosis and treatment, exhibiting dual anti-inflammatory and anti-viral properties.
- Brand names
- Henergy
- Other names
- ZQPZhengQiPianZhengqi Pian
02
Targets
EGFR (Epidermal growth factor receptor)MAPK14 (p38 mitogen-activated protein kinase alpha)MAPK3 (Mitogen-activated protein kinase 1)JNK (Mitogen-activated protein kinase kinase kinase family)STAT3 (Signal Transducer and Activator of Transcription 3)RdRp (Coronavirus RNA-dependent RNA polymerase)Mpro (3C-like proteinase of SARS-CoV-2)
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