zhengqing fengtongning

Zhengqing Fengtongning is a traditional Chinese medicine (TCM) preparation whose primary active ingredient is sinomenine hydrochloride. It is available in both tablet and injection forms. Sinomenine is an alkaloid extracted from the plant Sinomenium acutum and exhibits immunosuppressive and anti-inflammatory properties. The drug has been widely used in China for the treatment of autoimmune and inflammatory diseases such as rheumatoid arthritis (RA), lumbar disc herniation, cervical spondylosis, osteoarthritis, chronic nephritis, rheumatism, and gout. Mechanistically, it acts by modulating immune responses and reducing inflammation through multiple targets relevant to these conditions[1][2][5][6]. Clinical studies have shown that when combined with methotrexate for RA or with urate-lowering therapy for gout prophylaxis, it can improve clinical outcomes compared to monotherapy[2][5][6]. Adverse effects are generally mild but may include skin reactions such as flushing or rash[4].

Brand names

ZhengQingFengTongNingZheng Qing Feng Tong NingZQFTN

Other names

sinomenine hydrochloride preparationZhengqing Fengtongning InjectionZhengqing Fengtongning Tablets