Zhengxintai Capsule

Zhengxintai is a traditional Chinese medicine cardio-renal formula marketed primarily as Zhengxintai Capsule or tablet, used to improve kidney function and to treat coronary atherosclerotic heart disease, coronary artery disease, and angina. It is an SFDA-approved, prescription Chinese patent medicine included on China’s National Drug Reimbursement List and/or Essential Drug List, reflecting recognized clinical use in cardiovascular disease management. Mechanistically, Zhengxintai is a multi-component herbal formulation that exerts “multi-link, multi-target” actions typical of TCM cardio-cerebrovascular drugs, including vasodilation, improvement of microcirculation and hemorheology, antiplatelet and antithrombotic effects, antioxidant and anti-inflammatory activity, and protection of vascular endothelial cells and myocardium, thereby improving myocardial ischemia and relieving angina. Network pharmacology and systems pharmacology analyses of Zhengxintai Formula in coronary atherosclerotic heart disease suggest modulation of pathways related to inflammation, oxidative stress, apoptosis, and vascular function, although a single dominant molecular target has not been clearly defined.

Brand names

Zhengxintai CapsuleZhengxintai tablet

Other names

ZhengxintaiZhengxintai FormulaZXT