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Zhengzhou Univ. FAK compound 12s
- Development stage
- Preclinical
- Lead developer
- Zhengzhou University
01
Overview
Zhengzhou Univ. FAK compound 12s: sourced facts only. name: "Among them, compound 12s displayed potent inhibitory potency on FAK (IC50 = 47 nM), and demonstrated more significant antiproliferative activities in MGC-803, HCT-116 and KYSE30 cells (IC50 values were 0.24, 0.45 and 0.44 μM, respectively) compared to TAE-226." [PMID:37797456]; target: "Among them, compound 12s displayed potent inhibitory potency on FAK (IC50 = 47 nM), and demonstrated more significant antiproliferative activities in MGC-803, HCT-116 and KYSE30 cells (IC50 values were 0.24, 0.45 and 0.44 μM, respectively) compared to TAE-226." [PMID:37797456]; developer: "School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou 450001, China." [PMID:37797456]; stage: "In conclusion, compound 12s emerges a potent FAK inhibitor that could exert potent inhibitory activity against gastric cancer cells." [PMID:37797456]
02
Targets
FAK (Focal adhesion kinase)
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