Zhengzhou Univ. METTL3 compound 16e

Zhengzhou Univ. METTL3 compound 16e: sourced facts only. name: "The representative compound 16e showed an IC50 value of 0.49 ± 0.30 nM against METTL3." [PMID:40939495]; target: "The representative compound 16e showed an IC50 value of 0.49 ± 0.30 nM against METTL3." [PMID:40939495]; developer: "Department of Pharmacy, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, China; Henan Key Laboratory of Precision Clinical Pharmacy, Zhengzhou University, Zhengzhou, 450052, China; Henan Sino-US International Joint Laboratory of Clinical Pharmacy, Zhengzhou, 450052, China." [PMID:40939495]; stage: "Additionally, compound 16e showed favorable pharmacokinetic characteristics and good antitumor efficacy in a SKOV3 xenograft model." [PMID:40939495]