Zhengzhou Univ. Skp2 compound E35

Zhengzhou Univ. Skp2 compound E35: sourced facts only. name: "Among them, E35 demonstrated excellent inhibitory activities against the binding of Skp2-Cks1." [PMID:39285177]; target: "Among them, E35 demonstrated excellent inhibitory activities against the binding of Skp2-Cks1." [PMID:39285177]; developer: "Tianjian Laboratory of Advanced Biomedical Sciences, Academy of Medical Sciences, Laboratory Animal Center, State Key Laboratory of Esophageal Cancer Prevention & Treatment, Zhengzhou University, Zhengzhou, Henan Province 450052, P. R. China." [PMID:39285177]; modality: "Herein, we present the design and optimization of a series of [1,2,4]triazolo[1,5-a]pyrimidine-based small molecules targeting Skp2." [PMID:39285177]; stage: "Furthermore, compound E35 showed an obvious inhibitory effect on MGC-803 xenograft mice without obvious toxicity." [PMID:39285177]