Drug intelligence / Profile preview

Zhenlong Xingnao Capsule

Development stage
Preclinical
Lead developer
Jinha Tibetan Medicine
Modality
Small Molecules
Administration
Oral
01

Overview

Zhenlong Xingnao Capsule (ZXC) is a Tibetan medicine formulation used primarily for the treatment of ischemic stroke. Preclinical studies have demonstrated that ZXC exerts neuroprotective effects in both in vitro and in vivo models of cerebral ischemia-reperfusion injury. The mechanism of action involves reducing reactive oxygen species (ROS), modulating amino acid neurotransmitter levels, and regulating the expression of apoptosis-related proteins such as Bcl-2, Bax, caspase-3, p38 MAPK, and nuclear factor kappa B (NF-κB). These actions contribute to improved antioxidant capacity and reduced neuronal damage during ischemic events[1].

Brand names
Zhenlong Xingnao Capsule
Other names
ZXC
02

Targets

NF-κBRK (Ribokinase)CASP3 (Caspase-3)

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