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Zhenzhu Mingmu Diye
- Development stage
- Unknown
- Lead developer
- Tianlong Pharmacy
- Modality
- Small Molecules
- Administration
- Ophthalmic
01
Overview
Zhenzhu Mingmu Diye, also known as Pearl Mingmu eye drops, is a traditional Chinese medicine (TCM)-based ophthalmic formulation primarily used to treat visual fatigue, chronic conjunctivitis, and dry eye syndrome. The drug is a combination product containing Margarita liquid (pearl hydrolysate) and Borneolum Syntheticum (synthetic borneol). It is often formulated as a colloidal solution to improve the stability and dispersion of its active components, thereby extending the residence time on the ocular surface and enhancing absorption. Mechanistically, the borneol component acts as an agonist of the Transient Receptor Potential Melastatin 8 (TRPM8) channel, which is believed to stimulate tear secretion and provide a cooling, soothing effect. The pearl hydrolysate provides essential amino acids and trace elements that support ocular tissue health. The product is developed and manufactured by several entities, including Suzhou Industrial Park Tianlong Pharmacy Co., Ltd. and Suzhou Lezhu Pharmaceutical Co., Ltd.
- Brand names
- Zhenzhu Mingmu DiyePearl Mingmu Eye Drops
- Other names
- Margarita and Borneolum Eye DropsZhenzhu Mingmu Diyanye
02
Targets
TRPM8 (Transient receptor potential cation channel subfamily M member 8)
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