Drug intelligence / Profile preview

zhibai dihuang wan

Development stage
Unknown
Lead developer
Shaanxi Tianyang Pharmaceutical
Administration
Oral
01

Overview

Zhibai Dihuang Wan is a classic Traditional Chinese Medicine (TCM) formula derived from Liuwei Dihuang Wan with the addition of Anemarrhena asphodeloides (Zhimu) and Phellodendron amurense (Huangbai). It is primarily used to treat yin deficiency with vigorous fire (yin xu huo wang), characterized by symptoms such as night sweats, dry mouth, sore throat, and tinnitus. In clinical research, it has been investigated for its efficacy in treating recurrent oral ulcers, gingivitis, dry eye, and central precocious puberty in children. The formula works by nourishing kidney yin and clearing heat, modulating the immune and endocrine systems through its complex botanical constituents.

Brand names
Zhibai Dihuang Wan
Other names
Zhibai Dihuang pills知柏地黄丸
02

Targets

AKT1 (Proto-oncogene serine/threonine-protein kinase Akt1)

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