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zhibitai
- Development stage
- Phase 2
- Lead developer
- Chengdu Diao Jiuhong Pharmaceutical
- Modality
- Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules
- Administration
- Oral
01
Overview
Zhibitai is a Chinese patent medicine formulated as an oral capsule, primarily used for the treatment of hyperlipidemia and related cardiovascular conditions. It is composed of a family of naturally occurring statins derived from traditional Chinese medicinal ingredients. The main mechanism involves lipid-lowering effects similar to those of conventional statins, reducing total cholesterol (TC), triglycerides (TG), and low-density lipoprotein cholesterol (LDL-C), while increasing high-density lipoprotein cholesterol (HDL-C). Clinical studies have shown that Zhibitai can be used alone or in combination with conventional therapies such as atorvastatin, providing comparable efficacy in lipid management with a lower incidence of adverse events. It is widely used in China for patients intolerant to synthetic statins or seeking alternative therapies[1][3][7].
- Brand names
- Zhibitai
- Other names
- ZBTZhibitai capsule
02
Targets
HMGCR (3-hydroxy-3-methylglutaryl-coenzyme A reductase)
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