Drug intelligence / Profile preview

Zhichan Granule

Development stage
Unknown
Lead developer
Shanghai Municipal Hospital of Traditional Chinese Medicine
Administration
Oral
01

Overview

Zhichan Granule is a Traditional Chinese Medicine (TCM) herbal formulation developed by the Shanghai Hospital of Traditional Chinese Medicine, primarily indicated for the treatment of Parkinson's disease (PD). The preparation is intended to address both motor symptoms and non-motor complications, such as constipation, by modulating the gut microbiota and metabolic profiles. Research suggests that the granule may exert neuroprotective effects and improve gastrointestinal function through the gut-brain axis. It is typically administered as an oral granule formulation and is often used as an adjunctive therapy to standard levodopa treatment to improve clinical outcomes and reduce complications.

Other names
Zhichan Decoction
02

Targets

MAOB (Monoamine oxidase B)TH (Tyrosine hydroxylase)

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