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Zhile Capsule (知乐胶囊) is a Traditional Chinese Medicine (TCM) candidate developed by Zhejiang Shiqiang Pharmaceutical for the treatment of major depressive disorder (MDD). It is specifically formulated to address the TCM syndrome pattern of Qi and Yin deficiency with liver stagnation transforming into heat. The drug is currently undergoing clinical evaluation in China (e.g., trial CTR20244526) to assess its therapeutic efficacy and safety profile in patients with depression. As a botanical formulation, it likely exerts its effects through the synergistic action of multiple small molecule components derived from herbal extracts.
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