Drug intelligence / Profile preview

Zhisou

Development stage
Unknown
Lead developer
Shantou Central Hospital
Administration
Oral
01

Overview

Zhisou (specifically Zhisou Oral Liquid or Mixture) is a Traditional Chinese Medicine (TCM) hospital preparation developed by Shantou Central Hospital for the treatment of small airway disease (SAD). Small airway disease is characterized by inflammation and obstruction of the peripheral airways with an internal diameter of less than 2 mm, often serving as an early pathological indicator for chronic obstructive pulmonary disease (COPD) or asthma. The formulation is based on Traditional Chinese Medicine principles aimed at ventilating the lungs, relieving cough, and resolving phlegm. Clinical studies conducted by the developer have demonstrated that Zhisou improves small airway function parameters, including maximal mid-expiratory flow (MMEF) and forced expiratory flow at 50% and 75% of vital capacity (FEF50, FEF75), while reducing airway hyperresponsiveness and local inflammation.

Brand names
Shanhaidan
Other names
Zhisou Oral LiquidZhisou Mixture止嗽口服液止嗽合剂
02

Targets

BCL-2 (BCL-2 family)TRPA1 (Transient receptor potential cation channel subfamily A member 1)TRPV1 (Transient receptor potential cation channel subfamily V member 1)ADRB2 (β2)ICAM1 (Intercellular Adhesion Molecule 1)MAPK3 (Mitogen-activated protein kinase 1)AKT1 (Proto-oncogene serine/threonine-protein kinase Akt1)FOS (Activator Protein 1)

Beyond the preview

Go deeper on Zhisou.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Clinical trials

Full profile access

Follow clinical development from study design and recruitment through results.

  • Trial phase
  • Status
  • Readouts

Indications & development

Full profile access

Explore development by indication, patient population, and geography.

  • Indications
  • Development status
  • Countries

Licensing & deals

Full profile access

Trace asset ownership, licensing agreements, and commercial partnerships.

  • Partners
  • Deal terms
  • Milestones

Patents & exclusivity

Full profile access

Explore the patent landscape and regulatory exclusivity around an asset.

  • Patents
  • Expiration dates
  • Exclusivity

Competitive landscape

Full profile access

Compare development programs by target, modality, and indication.

  • Competing assets
  • Targets
  • Development stage

Research & analysis

Full profile access

Connect source evidence and development news to your research questions.

  • Publications
  • News
  • Analysis

Bring the full picture into focus.

See how Gosset can support your research on Zhisou.

Explore the full profile

Gosset Free

Get started with Gosset.

Enter your work email and we’ll be in touch with next steps.

Work email preferred.

Book a call