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Zhisuixin

Development stage: Unknown
Lead developer: The Affiliated Brain Hospital of Guangzhou Medical University
Modality: Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
Administration: Oral

Overview

Zhisuixin is a Traditional Chinese Medicine (TCM) granule formulation developed by The Affiliated Brain Hospital of Guangzhou Medical University. It is currently being investigated for the treatment of subthreshold depression in adolescents. The drug is evaluated in clinical trials for its efficacy and safety in improving a range of symptoms, including depressive mood, anxiety, sleep disturbances, fatigue, and cognitive impairment. As a multi-component herbal intervention, Zhisuixin is designed to address the complex pathophysiology of early-stage depressive disorders, and ongoing research aims to identify specific mechanistic biomarkers associated with its therapeutic effects.

Other names: Zhisuixin granule

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