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Zhitongzhu decoction
- Development stage
- Unknown
- Lead developer
- The First Affiliated Hospital of Heilongjiang University of Chinese Medicine
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
Zhitongzhu decoction is a Traditional Chinese Medicine (TCM) herbal formulation developed by the First Affiliated Hospital of Heilongjiang University of Chinese Medicine for the treatment of ankylosing spondylitis (AS). In the context of TCM, it is used to treat 'Bi syndrome' characterized by kidney deficiency and cold-dampness, aiming to alleviate spinal pain, reduce joint stiffness, and improve physical mobility. The therapeutic mechanism of the decoction involves immunomodulatory and anti-inflammatory actions, specifically by suppressing the production of pro-inflammatory cytokines such as tumor necrosis factor-alpha (TNF-α) and interleukin-6 (IL-6). It is typically administered as an oral liquid and is utilized as a specialized hospital preparation in clinical practice in China.
- Other names
- Zhitong Zhubi decoctionZhitong Zhubi Tang
02
Targets
IL-6 (Interleukin 6)
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