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Zhixiao Decoction

Development stage: Preclinical
Lead developer: Shanghai Pudong New Area Health Commission
Administration: Oral

Overview

Zhixiao Decoction is a traditional Chinese herbal medicine formulation. The specific formulation, 'desensitization Zhixiao Decoction' (also known as Tuomin Zhiti decoction or TZD), is being investigated for the treatment of allergic rhinitis. While other formulations like Zhixiao Tang (ZXT) have been used for pneumonia, the general mechanism of action for Zhixiao Decoctions often involves anti-inflammatory and immunomodulatory effects, targeting pathways related to inflammation, immunity, and apoptosis.

Other names: desensitization Zhixiao DecoctionTuomin Zhiti decoctionTZDZhixiao TangZXT

Targets

MMP2 (Matrix metalloproteinase-2)SYK (Spleen Tyrosine Kinase)AKT1 (Proto-oncogene serine/threonine-protein kinase Akt1)

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