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Zhongyu 1 is a proprietary hospital-made traditional Chinese medicine (TCM) preparation developed by the Shanghai Dermatology Hospital for the treatment of psoriasis. Formulated primarily as an oral capsule, it is designed to address the blood-heat and blood-stasis patterns characteristic of psoriasis according to TCM theory. The preparation contains a complex mixture of herbal ingredients, such as *Rehmannia glutinosa* and *Salvia miltiorrhiza*, which work synergistically to cool the blood, clear heat, and promote blood circulation. Clinically, Zhongyu 1 is used to reduce skin lesion severity, alleviate itching, and modulate the immune response, often serving as a core component of the hospital's integrated treatment protocols for chronic plaque psoriasis.
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