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Zhuangyao Jianshen Wan (壮腰健肾丸) is a traditional Chinese medicine (TCM) formula classified as an over-the-counter herbal remedy. It is primarily used to "tonify the kidney and strengthen the waist," nourish blood, and dispel wind-dampness. The main indications include lower back pain due to kidney deficiency, weakness or soreness in the knees and lower limbs, frequent urination, rheumatic bone pain, and neurasthenia. The formula contains multiple herbal ingredients such as Cibotium barometz (狗脊), Spatholobus suberectus (鸡血藤), Morinda officinalis (牛大力), Taxillus chinensis (桑寄生), Ligustrum lucidum (女贞子), Euryale ferox seed (金樱子), Millettia root (千斤拔), Hypserpa nitida root ("黑老虎"), Cuscuta chinensis seed processed with salt ("菟丝子"), with honey as an excipient[4][7][8]. Its mechanism of action is based on TCM theory—supporting kidney yang/qi/blood and removing wind-dampness—but no specific molecular targets are established in modern pharmacology.
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