Drug intelligence / Profile preview

zhui feng tou gu wan

Development stage
Unknown
Lead developer
Tiandi Hengyi Pharmaceutical
Administration
Oral
01

Overview

Zhui Feng Tou Gu Wan is a traditional Chinese herbal formula composed of multiple herbs. It is used primarily for the relief of musculoskeletal pain conditions such as arthritis, back pain, joint pain and swelling, bone degeneration, weakness in the knees and legs, and trauma-related pain. According to traditional Chinese medicine (TCM) theory, it works by dispelling wind-cold-dampness from the body (a TCM concept), promoting blood circulation and Qi flow, nourishing Yin and Yang energies, reducing swelling and stiffness (ankylosis), warming the kidneys and liver systemically to strengthen muscles and bones. The formulation typically contains a blend of 14 or more herbs including Taxilli Herba (Chinese Mistletoe), Cyperi Rhizoma (Nut-Grass), Notopterygii Rhizoma et Radix (Notopterygium root/rhizome), Ligustici Rhizoma (Chinese Lovage), Eucommiae Cortex (Eucommia Bark), Achyranthis Bidentatae Radix (Achyranthes Root), Speranskiae Herba (Speranskia Herb/Tou Gu Cao), Paeoniae Radix Alba (White Peony Root/Bai Shao), Angelicae Dahuricae Radix (Purple Angelica/Bai Zhi), Dipsaci Radix (Japanese Teasel Root/Xu Duan), Glycyrrhizae Radix (Licorice/Gan Cao), Notoginseng Radix/Pseudoginseng Root/San Qi/Tian Qi/Notoginseng Panax notoginseng/Myrrha/Myrrh/Mo Yao/Olibanum/Frankincense/Ru Xiang/Poria/Fu Ling[2][3][5]. The mechanism of action is based on TCM principles rather than modern pharmacology; however some ingredients are known for anti-inflammatory or analgesic effects in biomedical research. It is available as pills or capsules from various manufacturers under different brand names[1][4][5].

Brand names
Baiyunshan Zhuifeng Tougu WanGolden Flower Chase Wind Penetrate Bone Formula
Other names
zhui-feng tou-gu追风透骨丸chase wind penetrate bone formulazhuifengtougu pill
02

Targets

MYD88 (Myeloid differentiation primary response protein MyD88)TLR2 (Toll-like Receptor 2)NF-κBTLR4 (Toll-like receptor 4)

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