Drug intelligence / Profile preview

Zicam Cough Mist

Development stage
Unknown
Lead developer
Matrixx Initiatives
Modality
Small Molecules
Administration
Oral
01

Overview

Zicam Cough Mist is an over-the-counter antitussive medication used for the temporary relief of coughs caused by minor throat and bronchial irritation, such as those associated with the common cold or inhaled irritants. The active ingredient is dextromethorphan hydrobromide, a non-opioid morphinan derivative that acts centrally on the cough center in the medulla oblongata. By elevating the cough threshold, it effectively suppresses the urge to cough without providing significant analgesic or sedative effects at therapeutic doses. Unlike many other products under the Zicam brand that are marketed as homeopathic cold remedies, Zicam Cough Mist is a conventional pharmaceutical formulation. It is typically administered as an oral spray, providing a convenient delivery method for immediate-release cough suppression.

Brand names
Zicam Cough MistZicam Cough MaxZicam Cough Max Mist
Other names
dextromethorphan hydrobromide
02

Targets

NMDAR (Glutamate receptor ionotropic, NMDA)SIGMAR1 (Sigma non-opioid intracellular receptor 1)

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