Drug intelligence / Profile preview

Zihua Wenfei granule

Development stage
Unknown
Lead developer
Yuekang Pharmaceutical
Modality
Small Molecules
Administration
Oral
01

Overview

Zihua Wenfei granule is a Traditional Chinese Medicine (TCM) herbal formulation developed by the Guangdong Province Traditional Chinese Medical Hospital for the treatment of post-infectious cough (PIC). It is specifically indicated for patients presenting with the TCM syndrome of cold-phlegm obstructing the lung, which typically manifests as a persistent cough following an acute respiratory tract infection. The formulation is composed of several botanical extracts, including *Peucedanum decursivum* (Zihua Qianhu), *Aster tataricus* (Ziwan), and *Tussilago farfara* (Kuandonghua), which are traditionally used to ventilate the lungs, dispel cold, and resolve phlegm. Clinical studies, including Phase 2 and Phase 3 trials in China, have evaluated its efficacy in reducing cough frequency and severity by modulating airway inflammation and reducing cough reflex sensitivity.

Brand names
Zihua Wenfei granule
Other names
Zihua Wenfei Keli紫花温肺颗粒

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