zinc + cholecalciferol

**zinc + cholecalciferol** is a dietary supplement combining the mineral zinc with cholecalciferol, the form of vitamin D3. This combination is primarily used to prevent and manage deficiencies of these nutrients and is commonly indicated for supporting bone health, reducing risk of osteoporosis, aiding prevention of rickets and osteomalacia, supporting healthy muscles, teeth, and immune system, and promoting wound healing and tissue repair[1][7][8]. - **Mechanism of action:** - *Cholecalciferol* increases intestinal absorption of calcium and phosphorus, modulates bone metabolism, and supports immune function by activating the vitamin D receptor to regulate gene expression involved in mineral homeostasis and immune responses[3][7][8]. - *Zinc* acts both as a cofactor for vitamin D function and is required for proper immune response, DNA synthesis, cell division, and tissue repair[8]. Zinc modulates the vitamin D receptor’s (VDR) DNA binding via zinc finger domains, enabling effective transcriptional responses by vitamin D-dependent genes[8]. - The combination does not have a direct effect on mood or emotions and is not addictive[1]. - Available in oral formulations including tablets, capsules, chewable tablets, effervescent tablets, and liquid suspensions[1].

Other names

zinc + vitamin D3zinc + cholecalciferol