zinc citrate + dipotassium glycyrrhizinate

Zinc citrate + dipotassium glycyrrhizinate is a combination pharmaceutical product developed by the Third Affiliated Hospital of Southern Medical University for the treatment of oral inflammatory diseases, specifically gingivitis and periodontitis. Zinc citrate serves as an antimicrobial and anti-plaque agent; it releases zinc ions that inhibit bacterial metabolism, particularly glycolytic enzymes in oral pathogens like *Streptococcus mutans*, thereby reducing acid production and plaque accumulation. Dipotassium glycyrrhizinate, a salt derived from licorice root, provides potent anti-inflammatory and anti-allergic effects. It works by inhibiting the production of pro-inflammatory cytokines (such as TNF-alpha and IL-1beta) and may modulate the activity of 11-beta-hydroxysteroid dehydrogenase to enhance local anti-inflammatory responses. Together, the combination aims to control the bacterial load while simultaneously soothing inflamed gingival tissues.

Other names

compound zinc citrate and dipotassium glycyrrhizinatezinc citrate and dipotassium glycyrrhizinate combination