Drug intelligence / Profile preview

zinc sulfate heptahydrate

Development stage
Approved
Modality
Small Molecules
Administration
Oral, Intraperitoneal, Topical
01

Overview

Zinc sulfate heptahydrate is an inorganic salt and a common crystalline form of zinc sulfate. It serves as a critical source of bioavailable zinc ions (Zn2+), which are essential micronutrients involved in numerous physiological processes, including DNA synthesis, protein metabolism, and immune system regulation. In clinical medicine, it is primarily used to treat and prevent zinc deficiency. Beyond its role as a nutritional supplement, research has demonstrated its potential anti-inflammatory effects; for instance, in animal models of intracranial aneurysms, zinc administration has been shown to suppress aneurysm growth by inducing the expression of A20 (TNFAIP3), a protein that inhibits the NF-κB signaling pathway. It is also widely utilized in agricultural applications for crop biofortification and as a precursor in the green synthesis of zinc oxide nanoparticles for antimicrobial and industrial uses.

Brand names
SolvazincZincomedZinvit
Other names
zinc sulfate (7H2O)zinc(II) sulfate heptahydratewhite vitriolZnSO4·7H2O
02

Targets

TNFAIP3 (Tumor necrosis factor alpha-induced protein 3)

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