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Zingiber officinale extract, commonly known as ginger extract, is a botanical preparation derived from the rhizome of the ginger plant. It contains bioactive compounds, primarily gingerols and shogaols, which are recognized for their antiemetic and gastroprotective properties. In the context of clinical research led by the Fundação Educacional Serra dos Órgãos, this extract is being evaluated for the management of motion sickness. Its mechanism of action involves the antagonism of 5-HT3 and muscarinic receptors, which helps suppress the vomiting reflex and modulate gastric dysrhythmias often associated with motion-induced nausea.
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