Clinical trials
Full profile accessFollow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
zingiber ottensii essential oil
- Development stage
- Preclinical
- Modality
- Small Molecules
- Administration
- Topical, Oral
01
Overview
Zingiber ottensii essential oil is a natural extract derived from the rhizomes of the Zingiber ottensii Valeton plant, a member of the Zingiberaceae family native to Southeast Asia. Preclinical research indicates that this essential oil possesses potent anti-cancer properties, specifically demonstrated against human cervical cancer (HeLa) cells. Its mechanism of action involves the induction of apoptosis through the activation of caspase-3 and the downregulation of anti-apoptotic proteins like Mcl-1. Furthermore, the oil inhibits key survival and growth signaling pathways, including the Mitogen-Activated Protein Kinase (MAPK) and Phosphoinositide 3-kinase (PI3K)/AKT cascades. It also suppresses the production of Interleukin-6 (IL-6), a cytokine that typically promotes tumor progression and chemoresistance in cervical malignancies. Safety evaluations have been conducted in zebrafish embryos and rat models, suggesting potential for further therapeutic development.
- Other names
- ZO essential oilZingiber ottensii Valeton essential oil
02
Targets
AKT1 (Proto-oncogene serine/threonine-protein kinase Akt1)IL-6 (Interleukin 6)
Beyond the preview
Go deeper on zingiber ottensii essential oil.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Full profile accessExplore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Full profile accessTrace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Full profile accessExplore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Full profile accessCompare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Full profile accessConnect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on zingiber ottensii essential oil.