zipeprol

Zipeprol is a centrally acting, non-opioid cough suppressant (antitussive) developed in France in the 1970s. Unlike codeine and dextromethorphan, it is not a morphinan derivative. Zipeprol acts primarily by influencing the cough center in the brainstem, providing antitussive effects through central mechanisms. It also exhibits local anesthetic, mucolytic, antihistamine, anticholinergic, and bronchospasmolytic properties. Zipeprol does not cause respiratory depression or constipation typical of opioid antitussives and has little to no analgesic activity at therapeutic doses; however, at high doses it may act as a weak opioid agonist and can induce dependence with withdrawal symptoms similar to opiates. The drug has been discontinued in Europe but remains available in some Asian and South American countries[1][5][6][7][8].

Brand names

ZinoltaRespileneAntituxil-ZChilvaxDelaviralDovavixinJactusEritosMirsolOgylineRespiraseRespirexSanotusSantusSilentosSousibimTalasaTusigenTussiflexZitoxil

Other names

zipeprol [INN:DCF]