zirconium-89-labeled RO5479599

Zirconium-89-labeled RO5479599 is a radiolabeled monoclonal antibody designed for immunoPET imaging. The antibody targets HER3 (human epidermal growth factor receptor 3), which is overexpressed in various solid tumors. By labeling the antibody with the positron-emitting radioisotope zirconium-89, this agent enables non-invasive visualization and quantification of HER3 expression in tumors using PET imaging. This approach supports patient selection and monitoring of therapeutic response in clinical trials involving anti-HER3 therapies. The primary indication studied has been metastatic and/or locally advanced malignant HER3-positive solid tumors of epithelial cell origin[2][9].

Other names

zirconium-89-labeled RO5479599zirconium89-labeled RO5479599zirconium 89-labeled RO547959989Zr-RO5479599